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Boosting the Power of Cancer-killing T-cells
CRISPR-edited T-cells could be a thousand times better at seeing and killing cancer than T-cells prepared using the current methodology.
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New Cell-weighing Technique Helps Predict How Drugs Affect Cancer Cells
Researchers at MIT have now shown that they can use a new type of measurement to predict how drugs will affect cancer cells taken from multiple-myeloma patients.
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Researchers Discover Mutation That Appears to Protect Against Multiple Aspects of Biological Aging
The first genetic mutation that appears to protect against multiple aspects of biological aging in humans has been discovered in an extended family of Old Order Amish living in the vicinity of Berne, Indiana, report Northwestern Medicine scientists.
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Defects in Cell’s ‘Waste Disposal System’ Linked to Parkinson’s
An international study has shed new light on the genetic factors associated with Parkinson’s disease, pointing at a group of lysosomal storage disorder genes as potential major contributors to the onset and progression of this common neurodegenerative disorder.
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Mouse Model Demonstrates Potential of New Autism Drug
Scientists have performed a successful test of a possible new drug in a mouse model of an autism disorder. The candidate drug, largely corrected electrical, behavioral and brain abnormalities in the mice.
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Potential Genetic Mechanism Behind Obesity Identified
New research from the Research Triangle suggests that variants in a gene called ankyrin-B -- carried by millions of Americans -- could cause people to put on pounds through no fault of their own.
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Interleukin 11: Responsible for Fibrosis and Causes Organ Damage
Researchers from Duke-NUS Medical School (Duke-NUS) and the National Heart Centre Singapore (NHCS) have discovered that a critical protein, known as interleukin 11 (IL11) is responsible for fibrosis and causes organ damage.
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CRISPR Delivery System Enables Deletion of Disease-causing Genes
MIT researchers have developed nanoparticles that can deliver the CRISPR genome-editing system and specifically modify genes in mice.
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Attacking Telomeres Offers First Effective Glioblastoma Therapy
Blocking TRF1 – a telomere protector – interrupts tumour growth and increases survival in various mouse models of glioblastoma.
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Next-generation Optogenetic Molecules Used to Control Single Neurons
The focused laser beam could help scientists map connections among neurons that underlie behavior.
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