Bioethics Council Rules Heritable Genome Editing "Ethically Acceptable" In Certain CircumstancesNews
A leading UK bioethics advisory body has weighed in on the debate around human genetic modification, concluding that heritable genome editing – modifying the DNA of an egg, sperm or embryo with changes that will be passed on to future generations – could be ‘morally permissible’ in humans, provided key ethical tests are met.
Hay Fever Risk Genes Overlap with Autoimmune DiseaseNews
In a large international study involving almost 900,000 participants, researchers from the University of Copenhagen and COPSAC have found new risk genes for hay fever. It is the largest genetic study so far on this type of allergy, which affects millions of people around the world.READ MORE
ExPecto Patronum! Magical Machine Learning Tool Summons DNA Dark Matter DataNews
A new machine learning framework, dubbed ExPecto, can predict the effects of mutations in the so-called “dark matter” regions of the human genome. ExPecto pinpoints how mutations can disrupt the way genes turn on and off throughout your body.
CRISPR Causes More Genome Damage Than First ThoughtNews
Researchers have discovered that CRISPR/Cas9 gene editing can cause greater genetic damage in cells than was previously thought. These results create safety implications for gene therapies using CRISPR/Cas9 in the future as the unexpected damage could lead to dangerous changes in some cells.
Damage to DNA is a daily occurrence but one that human cells have evolved to manage. Now researchers have determined how one DNA repair protein gets to the site of DNA damage. The authors hope this discovery will help identify new therapies for ovarian cancer.READ MORE
On July 17, 2014, a crowdfunding effort paid over $22,000 to have the floating water fern Azolla filiculoides sequenced. Four years later, the results are in.READ MORE
Funding will support development of a novel enzymatic process for DNA synthesis in collaboration with Durham University.READ MORE
Scientists have identified a new gene that plays a critical role in regulating the body's immune response to infection and disease. The discovery could lead to the development of new treatments for influenza, arthritis and even cancer.READ MORE
New research provides insights into an underlying mechanism that could explain why new cancer therapies to help treat metastatic melanoma do not always work on patients, paving the way for predicting which patients will benefit from certain drugs.
In pigs, endocrine disruptors can alter gene expression in a way that also affects the next generation. This has been shown by a team of researchers from ETH Zurich and the Technical University of Munich. The study findings could potentially apply to humans, too.READ MORE
Why do individuals respond differently to the same environment? Researchers have pinpointed a genetic difference in zebrafish tied to differing responses to the same environmental chemical. The work could have implications for identifying genetic factors that explain differential chemical sensitivity.