$3.6 Million to Study Adverse Effects of Genome EditingNews
As genome editing technologies advance toward clinical therapies, they are raising hopes of a completely new way to treat disease. However, challenges need to be addressed before potential treatments can be widely used in patients. To tackle these challenges, the National Institutes of Health has launched the Somatic Cell Genome Editing program, which has awarded multiple grants including more than $3.6 million to assess the safety of genome editing in human cells and tissues.
An insulin-binding protein in fruit flies could provide new opportunities for tackling mosquitoes that carry diseases such as malaria and yellow fever, scientists at the University of York have found.
Ever wonder why things that normally feel gentle, like putting on soft shirts, are painful after a sunburn? In a study of four patients with a rare genetic disorder, NIH researchers found that PIEZO2 may be responsible for tactile allodynia: the skin’s reaction to injury that makes normally gentle touches feel painful.READ MORE
Researchers say they have discovered a gene mutation that slows the metabolism of sugar in the gut, giving people who have the mutation a lower risk of diabetes, obesity, heart failure, and even death. The researchers say their finding could provide the basis for drug therapies that could mimic the workings of this gene mutation.
A new study from the Scripps Research laboratory of Sathyanarayanan Puthanveettil, PhD, peers deep within the nucleus of developing brain cells and finds that long noncoding RNAs play an important role in the healthy functioning and maintenance of synapses, the communication points between nerve cells in the brain.READ MORE
Understanding how physical organization of cells influences their identity is necessary for creating better organoids.READ MORE
In a new study that ultimately analyzed the genomes of nearly a quarter of a million men, a research team including UC San Francisco scientists has discovered that variants at a single site on Chromosome 6 are associated with a significantly higher risk of developing erectile dysfunction (ED).READ MORE
Scientists have discovered a gene that appears to play a vital role in pheromone sensing. The gene is conserved across fish and mammals and over 400 million years of vertebrate evolution, indicating that the pheromone sensing system is much more ancient than previously believed.