Bioethics Council Rules Heritable Genome Editing "Ethically Acceptable" In Certain CircumstancesNews
A leading UK bioethics advisory body has weighed in on the debate around human genetic modification, concluding that heritable genome editing – modifying the DNA of an egg, sperm or embryo with changes that will be passed on to future generations – could be ‘morally permissible’ in humans, provided key ethical tests are met.
Hay Fever Risk Genes Overlap with Autoimmune DiseaseNews
In a large international study involving almost 900,000 participants, researchers from the University of Copenhagen and COPSAC have found new risk genes for hay fever. It is the largest genetic study so far on this type of allergy, which affects millions of people around the world.READ MORE
ExPecto Patronum! Magical Machine Learning Tool Summons DNA Dark Matter DataNews
A new machine learning framework, dubbed ExPecto, can predict the effects of mutations in the so-called “dark matter” regions of the human genome. ExPecto pinpoints how mutations can disrupt the way genes turn on and off throughout your body.
CRISPR Causes More Genome Damage Than First ThoughtNews
Researchers have discovered that CRISPR/Cas9 gene editing can cause greater genetic damage in cells than was previously thought. These results create safety implications for gene therapies using CRISPR/Cas9 in the future as the unexpected damage could lead to dangerous changes in some cells.
Caveman organoid research is in the works to unlock the reason for the demise of the NeanderthalsREAD MORE
A tremendous amount of genetic material must be packed into the nucleus of every cell—a tiny compartment. By what means are certain regions of this packaged DNA unpackaged and used to manufacture RNA and proteins? New work has shed light on this process, with implications for certain age-related diseases and organ decay.READ MORE
A fairly simple test significantly improves the identification of bladder tumors that will likely become invasive.READ MORE
Genetic ancestry tests are often advertised as a tool to uncover new connections to diverse cultures and ancestries, but new research from the University of British Columbia has found people tend to pick and choose which races they identify with based on preconceived biases.
Researchers have discovered that the process of copying DNA generates a brake signal that stalls cell division. This molecular brake ensures that the cell has two complete copies of DNA before it divides and thus prevents DNA damage and cancer development.READ MORE
Changes in microRNA detected long before neurogeneration symptoms appear in miceREAD MORE
Researchers have identified the genetic structure of the Painted Bunting, a neotropical migratory songbird, using microsatellite DNA and single nucleotide polymorphisms to develop high-resolution markers to differentiate between individual birds, enabling identification of individual birds and migratory patterns.READ MORE
Transposons are DNA sequences that have the potential to move to new positions within the genome. Their mobilization in the genome of eggs and sperm can lead to infertility. An RNA-based defense system, the Piwi-interacting RNA (piRNA) pathway, is responsible for the suppression of transposons. A new study has advanced understanding of how Piwi fends off jumping genes.READ MORE
Genes located in a large chromosomal aberration associated with autism interact with each other to modulate the variable symptoms of the disease, according to new research.READ MORE