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A Molecular On/Off Switch for CRISPR

News   Mar 30, 2017 | Original story from The Scripps Research Institute

 
A Molecular On/Off Switch for CRISPR

This image shows how the CRISPR surveillance complex is disabled by two copies of anti-CRISPR protein AcrF1 (red) and one AcrF2 (light green). These anti-CRISPRs block access to the CRISPR RNA (green tube) preventing the surveillance complex from scanning and targeting invading viral DNA for destruction (Image from Lander Lab)

 
 
 

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Analysis & Separations Immunology & Microbiology

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