A Snapshot of the NGS Market — User Views
News Aug 21, 2013
The survey was designed to investigate current trends in NGS usage and determine future demands; to aid Oxford Gene Technology (OGT) in continuing to deliver high-quality, up-to-date services and provide insightful, relevant customer resources. The company received 596 responses from its worldwide database of contacts and donated to the UK charity DEBRA (for the genetic skin blistering condition Epidermolysis Bullosa) for each completed survey.
Responses on the most popular research areas for NGS and choice of methods uncovered a trend towards cost-effective, high-resolution targeted resequencing techniques over whole genome sequencing, with the Illumina platform identified as the leading technology. Cancer and rare disease are the most popular research areas for using NGS, supporting the use of targeted approaches which enable more accurate detection of rare variants.
Challenges in bioinformatics were found to be one of the biggest barriers to NGS implementation, which may explain why over a third of investigators choose to outsource data analysis. Supporting this finding, data quality and bioinformatics expertise are cited in the top three essential factors when choosing an NGS service provider.
Further insights into the use of NGS for clinical tests, preferred NGS methods, and demands on service providers are also presented. Download the full results here.
The survey adds to a growing portfolio of informative resources from OGT on NGS, including a recent whitepaper on choosing the right NGS method and a free-to-download demo version of their innovative and easy to use Genefficiency™ NGS reporting software.
Download the survey results or see below for more information on OGT’s Genefficiency services.
In a new study in cells, University of Illinois researchers have adapted CRISPR gene-editing technology to cause the cell’s internal machinery to skip over a small portion of a gene when transcribing it into a template for protein building. This gives researchers a way not only to eliminate a mutated gene sequence, but to influence how the gene is expressed and regulated.
Researchers published today a detailed description of the complete genome of bread wheat, the world's most widely-cultivated crop. This work will pave the way for the production of wheat varieties better adapted to climate challenges, with higher yields, enhanced nutritional quality and improved sustainability.