ACE Biosciences and Crucell Collaborate to Discover Antibody Therapies
News Nov 03, 2005
ACE BioSciencesA/S and Crucell N.V. have entered a research and licensing agreement to discover antibody therapies to combat serious hospital-acquired infections, including those caused by antibiotic-resistant bacteria.
Under the terms of the agreement, Crucell gains exclusive rights to assay a number of proprietary protein targets that ACE BioSciences has isolated and extracted from the cell surface of relevant bacteria.
Crucell will develop antibodies opposite these targets and in-licence the most promising ones for use in its anti-infection product development programme.
ACE BioSciences will be eligible for royalty and milestone payments on any therapies derived from the collaboration. ACE BioSciences was advised by BioSciencemanagers Ltd.
Ms Ingelise Saunders, ACE BioSciences’ CEO commented, "We are delighted that a company of the stature and experience of Crucell should recognize the unique therapeutic potential of our protein targets in the fight against infection."
"This deal validates the quality of our proteomics expertise and underlines the potential of our work in this large and underserved therapeutic area. I am confident that this is the first of a number of deals which we will broker in the coming months."
Researchers Awarded $28M for Illuminating Druggable Genome NIH GrantsNews
Researchers receive grants as part of the NIH program focused on experimental and informatics approaches to characterize understudied proteins from three gene families: ion channels, G protein-coupled receptors (GPCRs), and protein kinases.READ MORE
No Country for Old GenesNews
Our modern world is radically different from the one we evolved in, and that creates a mismatch between the environment our genes were evolved to face, and the world those genes now encounter. A new review looks at how certain genes that benefited humans in our genetic past now predispose us to disease in old age.READ MORE
CRISPR Editing Stops HIV Virus in Infected CellsNews
Human immunodeficiency virus-1 (HIV-1) infection is a chronic disease affecting more than 35 million people worldwide. The infection can be controlled by antiretroviral therapy (ART), but there is still no complete cure. Now, a new study targeting the regulatory genes of the virus using CRISPR/Cas9 has helped block the production of the virus by infected cells.READ MORE