We've updated our Privacy Policy to make it clearer how we use your personal data.

We use cookies to provide you with a better experience, read our Cookie Policy

© 2019 Technology Networks, all rights reserved

The Ancient History of Neandertals in Europe

News   Jun 27, 2019

Original story from Max Planck Institute for Evolutionary Anthropology

Femur of a male Neandertal from Hohlenstein-Stadel Cave, Germany. CREDIT © Oleg Kuchar, Museum Ulm

Parts of the genomes of two around 120,000-year-old Neandertals from Germany and Belgium have been sequenced at the Max Planck Institute for Evolutionary Anthropology in Leipzig, Germany. The analyses of these sequences showed that the last Neandertals, who lived around 40,000 years ago, trace at least part of their ancestry back to these European Neandertals that lived around 80,000 years earlier. The 120,000-year-old Neandertal from Germany, however, carried some ancestry that may originate from an isolated Neandertal population or from relatives of modern humans.

Researchers at the Max Planck Institute for Evolutionary Anthropology in Leipzig have retrieved nuclear genome sequences from the femur of a male Neandertal discovered in 1937 in Hohlenstein-Stadel Cave, Germany, and from the maxillary bone of a Neandertal girl found in 1993 in Scladina Cave, Belgium. Both Neandertals lived around 120,000 years ago, and therefore predate most of the Neandertals whose genomes have been sequenced to date.

Maxillary bone of a Neandertal girl from Scladina Cave, Belgium. CREDIT: © J. Eloy, AWEM, Archéologie andennaise.

By examining the nuclear genomes of these two individuals, the researchers could show that these early Neandertals in Western Europe were more closely related to the last Neandertals who lived in the same region as much as 80,000 years later, than they were to contemporaneous Neandertals living in Siberia. "The result is truly extraordinary and a stark contrast to the turbulent history of replacements, large-scale admixtures and extinctions that is seen in modern human history", says Kay Prüfer who supervised the study.

Intriguingly, unlike the nuclear genome, the mitochondrial genome of the Neandertal from Hohlenstein-Stadel Cave in Germany is quite different from that of later Neandertals – a previous report showed that more than 70 mutations distinguish it from the mitochondrial genomes of other Neandertals. The researchers suggest that early European Neandertals may have inherited DNA from a yet undescribed population. "This unknown population could represent an isolated Neandertal population yet to be discovered, or may be from a potentially larger population in Africa related to modern humans", explains Stéphane Peyrégne who led the analysis.

This article has been republished from the following materials. Note: material may have been edited for length and content. For further information, please contact the cited source.


Unraveling DNA Methylation Patterns Eases Introduction of Foreign DNA Into Host Cells


DNA methylation is catalyzed by a group of enzymes known as methyltransferases, which strategically decorate DNA with methyl groups in specific patterns. In a new study, scientists have developed a pipeline that allows for the identification of which enzyme causes which specific methylation pattern.


Children With a High Genetic Risk of Developing Type 1 Diabetes Have Different Gut Microbiomes


According to a new study, genetic risk can shape an individual's response to environmental factors in the development of autoimmune disease.


Optical Neural Networks Close the Gap on Their Electronic Counterparts


A new paper demonstrates distinct improvements to the inference and generalization performance of diffractive optical neural networks. Ultimately these improvements may provide major advantages for autonomous vehicles, robotics and various defense-related applications, among others.


Like what you just read? You can find similar content on the communities below.

Applied Sciences Informatics

Related Content