Applied Precision Showcases Cellular Imaging Lab at ASCB 2005
News Dec 13, 2005
Applied Precision, LLC has announced that it will feature the mobile Cellular Imaging Lab for North America and its enhanced version of the DeltaVision® RT Restoration Imaging System, during the 45th Annual American Society for Cell Biology (ASCB) meeting December 10th-14th.
ASCB attendees will also be able to review cellWoRx™ - Applied Precision's automated, 4-color High Content Cell Analysis System - now coupled with Cellomics' vHCS™ Analysis Toolbox to provide users with a turnkey solution, from advanced image acquisition to flexible image analysis.
The company will be introducing its mobile Cellular Imaging Lab for North America, a completely mobile working lab that showcases Applied Precision's advanced imaging capabilities for life science imaging and research.
Life science researchers attending the ASCB event at the Moscone Center in San Francisco can visit Applied Precision's Booth #913 to discover live-cell imaging capabilities, faster scanning times and improved sensitivities on a wide range of critical applications.
Applied Precision's DeltaVision RT, a fluorescence imaging system, designed to provide researchers with a single, integrated system engineered to meet their difficult imaging demands.
The DeltaVision RT utilizes high sensitivity Electron Multiplying Charge-Coupled Device (EMCCD) technology, enabling ultra low light fluorescence imaging with superior quantum efficiency.
Applied Precision claims that, combined with the high viability rapid shuttering, this not only increases acquisition speed but also reduces the risk of phototoxicity during live-cell imaging studies.
Utilizing a Quantifiable Laser Module (QLM), the addition of a Total Internal Reflection Fluorescence (TIRF) illuminator enables a signal-to-noise ratio for enhanced cell-surface event visualization at multiple wavelengths, while an improved environmental chamber further enhances the system's performance by sustaining cell viability for advanced live-cell imaging research.
cellWoRx is designed to provide researchers high resolution, contrast and signal-to- noise for optimal image quality.
It increases image contrast and minimizes fluorescence background by employing oblique illumination technology in place of traditional epi-fluorescent illumination.
The system also utilizes a white-light based CCD camera that delivers higher quantum efficiency than is possible with laser-based systems.
Image quality is further improved through constrained-iterative deconvolution software that reassigns captured light back to its point of origin.
In a new study in cells, University of Illinois researchers have adapted CRISPR gene-editing technology to cause the cell’s internal machinery to skip over a small portion of a gene when transcribing it into a template for protein building. This gives researchers a way not only to eliminate a mutated gene sequence, but to influence how the gene is expressed and regulated.
Researchers published today a detailed description of the complete genome of bread wheat, the world's most widely-cultivated crop. This work will pave the way for the production of wheat varieties better adapted to climate challenges, with higher yields, enhanced nutritional quality and improved sustainability.