Automation of Adherent Cell Culture Maintenance
News May 14, 2007
The demand for mammalian cells in pharmaceutical screening and cell biology research is constantly increasing. Limitations of the currently used cell culture procedures include lack of standardisation associated with poor reproducibility and insufficient throughput.
Hamilton, Life & Brain and University of Bonn have joined their expertise in the development of a system for the automated culture of primary cells, cell lines and embryonic stem cells which can provide high quality cells in large numbers.
Additionally no increase in spontaneous differentiation compared to the manual control can be observed – a definite indication for the gentle handling of cells by the robot.
With the automation of cell cultures, a reduction of manual workload for pharmaceutical and biotech companies comes into reach. The way is now open to further automation of cell lines like CaCo2 and downstream applications such as reporter gene assays.
Scientists have used machine learning to train computers to see parts of the cell the human eye cannot easily distinguish. Using 3D images of fluorescently labeled cells, the research team taught computers to find structures inside living cells without fluorescent labels, using only black and white images generated by an inexpensive technique known as brightfield microscopy.READ MORE
Back in 2009, researchers identified a herd of Awassi sheep suffering from "day blindness". As that term implies, these sheep were blind during the day (in bright light) but could see at night, in low-light conditions. After identifying the genetic basis of this blindness, researchers have now successfully used gene therapy to restore their daytime vision.READ MORE