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Autonomously Growing Synthetic DNA Strands

News   Nov 07, 2017 | Original story from Wyss Institute

 
Autonomously Growing Synthetic DNA Strands

Primer Exchange Reaction (PER) cascades enable the autonomous growth of single-stranded DNAs. On the top, a ‘catalytic PER hairpin’ binds a first ‘primer’ (shown as a short grey strand), triggers its elongation with a sequence encoded by the hairpin itself, and releases it to start another cycle with the already extended primer, and so forth, until a long transcript is generated. Credit: Wyss Institute at Harvard University

 
 
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