BioFocus DPI Enhances High-Throughput Screening Library
News Apr 24, 2009
BioFocus DPI, a leading provider of gene-to-drug candidate discovery services, announces that it has added 350,000 new compounds to its diverse screening library. Through these additional compounds, BioFocus DPI’s high-throughput screening platform now includes more than 900,000 compounds.
The 350,000 new compounds were selected to complement BioFocus DPI’s existing diverse screening library. By applying stringent lead-likeness criteria in its selection process, BioFocus DPI has enhanced the quality and diversity of its high-throughput screening library, offering a broader chemical space for customers’ hit finding campaigns.
“Combined with an extensive range of knowledge-based methodologies, this updated screening library allows BioFocus DPI customers to select optimal screening sets for their hit finding campaigns,” said Kate Hilyard, VP Biological Sciences. “This improved screening set, combined with leading-edge target class and assay development expertise, translates into one of the most powerful screening platforms in the industry.”
In a new study in cells, University of Illinois researchers have adapted CRISPR gene-editing technology to cause the cell’s internal machinery to skip over a small portion of a gene when transcribing it into a template for protein building. This gives researchers a way not only to eliminate a mutated gene sequence, but to influence how the gene is expressed and regulated.
Researchers published today a detailed description of the complete genome of bread wheat, the world's most widely-cultivated crop. This work will pave the way for the production of wheat varieties better adapted to climate challenges, with higher yields, enhanced nutritional quality and improved sustainability.