CBI Presents Data at Forensic Sciences Meeting Confirming Benefits of zyGEM’s DNA Extraction Technology
News Mar 05, 2009
ZyGEM Corp. Ltd. reported that researchers from Commonwealth Biotechnologies, Inc. (CBI) presented positive data on ZyGEM’s forensicGEM™ DNA extraction technology at the 2009 American Academy of Forensic Sciences (AAFS) Annual Meeting.
The data show that forensicGEM™ DNA extraction kits provide important benefits, including improved DNA yield from a variety of blood samples and buccal cell suspensions. Compared to other DNA extraction methods, forensicGEM™ kits yielded up to six times more DNA per sample than other commonly used methods.
ZyGEM’s forensicGEM™ family of kits uses a proprietary enzyme to extract DNA from samples using a single closed-tube system. Researchers at CBI’s Fairfax Identity Laboratories (FIL) DNA reference operations are collaborating with ZyGEM to further evaluate the kits and to help develop additional products for the forensic DNA market.
“The results we presented at the AAFS meeting show that the single closed-tube system used by ZyGEM’s forensicGEM™ kits offers certain improvements and efficiencies compared to other DNA extraction methods,” said Charles M. Kelly, Ph.D., Director of FIL and lead author of the AAFS study.
“We were able to produce PCR-ready DNA in just over 30 minutes with excellent reproducibility. forensicGEM™’s gentle extraction method does not appear to damage DNA and the closed-tube system minimizes the risk of contamination. These kits can be specially designed to be compatible with common STR genotyping profiling kits and forensic genotyping methods. The ability to accurately and easily extract high quality DNA by a cost-effective method is especially critical for our operations at FIL,” Kelly said.
The forensicGEM™ approach uses ZyGEM’s proprietary enzyme and a single closed-tube system to simplify laboratory workflow, minimize error, reduce the risk of contamination and ensure sample integrity, while also reducing costs. The kits are easy to automate for high-throughput applications using off-the-shelf robotic systems. They have been specifically formulated for DNA extraction from a range of different crime sample types without the need for further purification.
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