CEA Grants Roche License to Patent that Covers a Process for Synthesis of dsRNA
News Apr 13, 2006
The CEA has announced that its life science division has granted Roche Diagnostics GmbH, (Mannheim, Germany) a non-exclusive license under the patent family EP10618966.
This license concerns some RNAi products that Roche Diagnostics GmbH supplies to its customers in the research reagent field.
This patent family, owned solely by the CEA, covers a process for an enzymatic synthesis of double-stranded RNA based on the transcription of a double-stranded DNA template.
Double-stranded RNA triggers different types of gene silencing named RNA silencing or RNA interference. The application of RNA interference in mammals has the potential to allow therapeutic gene silencing.
Back in 2009, researchers identified a herd of Awassi sheep suffering from "day blindness". As that term implies, these sheep were blind during the day (in bright light) but could see at night, in low-light conditions. After identifying the genetic basis of this blindness, researchers have now successfully used gene therapy to restore their daytime vision.READ MORE