Celera and Ipsen Enter Research Collaboration to Develop Pharmacogenomic Tests
News Nov 21, 2007
Celera and Ipsen announced that they have entered into a research collaboration to develop biomarker and pharmacogenomic tests for growth failure patients. The initial phase of the collaboration will focus on the discovery and characterization of genetic markers relating to this disease.
Assuming the first phase of this collaboration is completed successfully, a key aim thereafter will be to develop diagnostic predictors for use in Ipsen’s clinical trials, which would potentially form the basis for commercial companion diagnostic tests for Ipsen’s short stature therapies.
Celera will receive an undisclosed payment for the initial phase of this multi-year collaboration, and any future payment will depend on success of the initial phase.
“We’re pleased to enter this collaboration with Ipsen as it further reinforces Celera’s pharmacogenomic endeavors,” said Thomas White, Ph.D., Chief Scientific Officer at Celera.
“This is another example highlighting the importance of diagnostic and pharmaceutical companies working together to improve therapeutic availability through the practice of personalized disease management,” White added.
“Celera’s leadership in the field of genomics as applied to diagnostic and prognostic assays is expected to support Ipsen’s effort towards the optimal use of its hormone replacement medicines for the treatment of short stature,” said Jacques-Pierre Moreau, Executive Vice-President, Chief Scientific Officer of Ipsen.
“The potential outcomes from this collaboration could lead to the development of tests to support the rationale for use of our products in novel indications for short stature.”
Scientists from the UNC School of Medicine discovered that the anti-inflammatory protein NLRP12 normally helps protect mice against obesity and insulin resistance when they are fed a high-fat diet. The researchers also reported that the NLRP12 gene is underactive in people who are obese, making it a potential therapeutic target for treating obesity and diabetes.READ MORE