Cenix BioScience Signs Research Agreement with Regulus Therapeutics for miRNA-Targeted Drug Discovery
News Jul 22, 2008
Cenix will apply its expertise in combining high throughput applications of small RNA-based gene silencing with high content phenotypic analyses in cultured human cells.
The company will thereby screen libraries of synthetic miRNA modulators designed and produced by Regulus, using multi-parametric assays to identify novel lead molecules offering highest therapeutic potential in the area of immunology and inflammation.
“Following the long-standing relationship and mutual respect shared with several key members of the starting team at Regulus, we at Cenix are very much looking forward to working together to drive this ground-breaking discovery program forward” said Dr. Christophe Echeverri, CEO/CSO of Cenix.
“Regulus is committed to discovering and developing novel microRNA-targeted therapeutics and adding to a large and growing body of knowledge on how individual microRNAs function within the cell,” said Peter S. Linsley, Ph.D. CSO of Regulus. “We look forward to working collaboratively with Cenix to identify interesting microRNA-targeted drug candidates.”
No further terms of the agreement were released.
Previous work by the International Multiple Sclerosis Genetics Consortium (IMSGC) has identified 233 genetic risk variants. However, these only account for about 20% of overall disease risk, with the remaining genetic culprits proving elusive. A new study has tracked down four of these hard-to-find genes.READ MORE
Scientists at McGill have found the answer to a question that perplexed Charles Darwin; if natural selection works at the level of the individual, fighting for survival and reproduction, how can a single colony produce worker ants that are so dramatically different in size – from “minor” workers to large-headed soldiers with huge mandibles – especially if they are sterile?