Chicago Research Scientists Launch Precision Biomarker Resources
News Apr 05, 2006
Precision provides microarray processing and data analysis services for pharmaceutical, biotechnology and academic researchers who use the latest methods for discovering biomarkers in their quest for new disease therapies. Precision uses the Affymetrix GeneChip® Microarray platform and is an Affymetrix Authorized Service Provider.
"Biomarker discovery is important in analyzing diseases and in predicting the performance of a drug during development, reducing uncertainties about effectiveness and safety and accelerating the preclinical process," said David B. Paul II, Ph.D., president of Precision Biomarker Resources.
"Microarrays allow researchers to analyze the effect of a drug or treatment on literally tens of thousands of genes simultaneously, enabling scientists to determine the exact mechanisms of a drug's effect on a disease," Dr. Paul added.
In addition, microarray comparisons of healthy and diseased genes yield information that can be used for more precise drug targeting and a clearer understanding of the causes of a disease, according to Eric G. Bremer, Ph.D., Precision's chief scientific officer.
"Last month, the Food and Drug Administration released a new Critical Path Opportunities report for modernizing biomedical discoveries that placed biomarker development at the top of the list, followed by streamlining clinical trial designs and bioinformatics," Dr. Bremer said. "Precision is poised to help with all three areas."
Precision builds on its principals' leadership in tumor studies and their commitment to advancing disease research. It was founded by the scientists who established and developed the Pediatric Brain Tumor Research Program at Children's, including Dr. Paul; Dr. Bremer; Jason Monroe, Precision's director of operations; and David George, the company's director of bioinformatics.
Dr. Bremer launched a microarray core facility at Children's in 1999 to support his tumor research and the work of other leading pediatric disease investigators. Precision team members have also conducted their own drug development.
The fifth founder is Charles C. Happ, Precision's business director, who is also board chairman of the Technology Innovation Center (TIC) incubator based in Evanston, whose alumni include Peapod Inc., IDEO, the Illinois Superconductor Corporation, and Surgical Insights.
3-D Printed Sugar Scaffolds Offer Sweet Solution for Tissue EngineeringNews
University of Illinois engineers built a 3-D printer that offers a sweet solution to making detailed structures that commercial 3-D printers can’t: Rather than a layer-upon-layer solid shell, it produces a delicate network of thin ribbons of hardened isomalt, the type of sugar alcohol used to make throat lozenges.READ MORE
Schizophrenics' Blood Contains RNA From More MicrobesNews
The blood of schizophrenia patients features genetic material from more types of microorganisms than that of people without the debilitating mental illness, research at Oregon State University has found. What’s not known is whether that’s a cause or effect of the severe, chronic condition that strikes about one person in 100.READ MORE
Faulty Gene Leads to Alcohol-Induced Heart FailureNews
A faulty gene interacts with alcohol to accelerate heart failure in susceptible patients, a study suggests. This dangerous interaction can occur even when only moderate amounts of alcohol have been consumed.READ MORE
Comments | 0 ADD COMMENT
2nd Annual Artificial Intelligence in Drug Development Congress
Sep 20 - Sep 21, 2018