Children’s National Medical Center to Investigate Diabetes Genetic Markers with OpenArray™ System
News Jan 17, 2008
BioTrove, Inc. has announced that researchers at the Children’s National Medical Center will use the BioTrove OpenArray™ SNP genotyping system to examine genes for diabetes-related traits, as well as to investigate genetic variants affecting skeletal muscle hypertrophy – the build-up of skeletal muscle tissue – with resistance training in multiple large populations.
“Research takes time and persistence to ensure accurate data, and when it comes to our young patients, we are seeking to speed up the clock while understanding how we can help. Children’s National is committed to finding innovative ways to address diseases affecting these young patients – including research into genetic indicators for certain conditions,” said Joseph Devany, Ph.D., assistant professor and head of the Genotyping Lab in the Research Center for Genetic Medicine at Children’s National Medical Center.
“Comparing thousands of samples across large populations would take several years with conventional methods. The high-throughput OpenArray system enables us to process samples in weeks instead of years, and its high accuracy helps conduct in-depth research without depleting our precious DNA samples,” said Eric Hoffman, Ph.D., Clark Professor of Pediatrics and director of the Research Center for Genetic Medicine at Children’s National.
Back in 2009, researchers identified a herd of Awassi sheep suffering from "day blindness". As that term implies, these sheep were blind during the day (in bright light) but could see at night, in low-light conditions. After identifying the genetic basis of this blindness, researchers have now successfully used gene therapy to restore their daytime vision.READ MORE