Chip-Man Technologies Ltd and ArcDia Ltd have announced a collaboration to develop fluorescence detection modules for integration with Chip-Man Technologies’ Cell-IQ® live cell culturing and analysis system.
The modules are designed to enable simultaneous measurement and analysis of cell events using both phase contrast and living dyes within the same culture under incubation.
Juha Korpinen, CEO, Chip-Man Technologies Limited said, "This development will greatly enhance the capabilities of the Cell-IQ to enable even more detailed information to be extracted from living cells."
He continued, "Professors Erkki Soini, Juhani Soini and colleagues are widely respected in the field of fluorescence detection. We are very fortunate to have such key expertise available within our local academic institutions."
The Cell-IQ software "learns" to recognize and record cellular change and to output these results as real time moving images and simple multi-parameter graphics.
The addition of a fluorescence detection module will enable the Cell IQ to identify specific siRNA and cDNA transcripts. This will allow them to be closely monitored and the resulting morphological changes recorded within the population.
Thus the measurement of the true rate of cellular stimulation to specific drugs will be possible.
In addition researchers can select out those fluorophores that minimally effect cells or have a synergistic or antagonistic effect on target drugs, enabling better optimization and control of cell based experimentation.