CRISP-Disp Leverages CRISPR-Cas9 to Deliver RNA Structures to Targets in the Genome

News Jun 10, 2015

The method enables the researchers to deliver artificial RNA devices — such as RNA processors, scaffolds, and imaging applications — to specific points on the genome. The work was led by John Rinn who, with his colleagues, is using the approach to better study long, non-coding RNAs (lncRNAs), which are hard to study using traditional knockout methods. With CRISP-Disp, the researchers can relocate lncRNAs to study them in isolation.

To learn more, read the team’s paper, which was published online by the journal Nature Methods.

New File Type Aims to Secure Genomic Data

News

Based on an analysis of data leakages and opportunities to prevent the potential misuse of genetic information, researchers have developed a new file format for functional genomics data that enables data sharing while protecting the personal information of research participants.

Marker May Help Target Treatments for Crohn’s Patients

News

Accurately predicting which subtype of Crohn's disease is likely to develop has not been possible, until now.

Breastfeeding Protects Babies from Antibiotic-resistant Bacteria

News

Babies that are breastfed for at least six months have less antibiotic-resistant bacteria in their gut compared with infants breastfed for a shorter time.

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