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CRISPR-Chip Detects Mutations in Minutes

News   Mar 25, 2019 | Original story from the Keck Graduate Institute

 
CRISPR-Chip Detects Mutations in Minutes

Kiana Aran's novel system immobilizes the CRISPR complexes on the surface of graphene-based transistors. These complexes search a genome to find their target sequence and, if the search is successful, bind to its DNA. This binding changes the conductivity of the graphene material in the transistor, which detects the change using a handheld reader. Credit: Keck Graduate Institute.

 
 
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