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CRISPR-Gold Fixes Duchenne Muscular Dystrophy Mutation in Mice

News   Oct 06, 2017 | Original story from UC Berkeley

 
CRISPR-Gold Fixes Duchenne Muscular Dystrophy Mutation in Mice

CRISPR–Gold is composed of 15 nanometer gold nanoparticles that are conjugated to thiol-modified oligonucleotides (DNA-Thiol), which are hybridized with single-stranded donor DNA and subsequently complexed with Cas9 and encapsulated by a polymer that disrupts the endosome of the cell. Credit: UC Berkeley

 
 
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