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CRISPR Reveals New Targets for Promising Cancer Drugs

News   Jul 20, 2017 | Original story from Harvard University

CRISPR Reveals New Targets for Promising  Cancer Drugs

redit: Haining Lab, Dana-Farber/Boston Children’s Genetic screening for cancer immunotherapy targets cancer cells (colored shapes), each with a different CRISPR-Cas9-mediated gene knocked out. T cells (red) destroy the cancer cells that have had essential immune evasion genes knocked out.



Analytical Tool Predicts Disease-Causing Genes


Predicting genes that can cause disease due to the production of truncated or altered proteins that take on a new or different function, rather than those that lose their function, is now possible thanks to an international team of researchers that has developed a new analytical tool to effectively and efficiently predict such candidate genes.


Researchers Move Closer to Completely Optical Artificial Neural Network


Researchers have shown that it is possible to train artificial neural networks directly on an optical chip. The significant breakthrough demonstrates that an optical circuit can perform a critical function of an electronics-based artificial neural network and could lead to less expensive, faster and more energy efficient ways to perform complex tasks such as speech or image recognition.


Single Gene Change in Gut Bacteria Alters Host Metabolism


Scientists have found that deleting a single gene in a particular strain of gut bacteria causes changes in metabolism and reduced weight gain in mice. The research provides an important step towards understanding how the microbiome – the bacteria that live in our body – affects metabolism.



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