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Diabetes Reversed in Mice With CRISPR-edited Stem Cells From Patients

News   Apr 23, 2020 | Original story from Washington University School of Medicine in St. Louis

 
Diabetes Reversed in Mice With CRISPR-edited Stem Cells From Patients

Researchers at Washington University School of Medicine in St. Louis have transformed stem cells into insulin-producing cells. They used the CRISPR gene-editing tool to correct a defect that caused a form of diabetes, and implanted the cells into mice to reverse diabetes in the animals. Shown is a microscopic image of insulin-secreting beta cells (insulin is green) that were made from stem cells produced from the skin of a patient with Wolfram syndrome. Credit: Millman lab Washington University.

 
 
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