Eisai & Genomics Plc Collaborate
News Apr 13, 2015
Eisai Co., Ltd. and Genomics plc have entered into a collaborative agreement to use Genomics' sophisticated statistical analyses of large-scale multi-phenotype genetic association data to inform Eisai's drug discovery process, including target selection, target validation, indication selection and repositioning.
Both companies believe that human genetics and genomics can add great value to the drug development process. Genomics, the Oxford based genome analytics company, will be partnering with Eisai's new Integrated Human Genomics (IHGx) Research Unit which operates directly under the supervision of Eisai Product Creation Systems' Chief Clinical Officer.
“Eisai is delighted to be working with Genomics,” states Dr. Nadeem Sarwar, Director of the IHGx Research Unit, “Genomics' founders are internationally recognized leaders in the analysis and interpretation of human genetic data. This collaboration is another indication of Eisai's commitment to leveraging genomic knowledge to accelerate the discovery and development of impactful new medicines.”
Professor Peter Donnelly, a director and founder of Genomics, says, “Genomics' research work with Eisai will demonstrate the real value that powerful analyses of large genomic databases can add to drug development pipelines.”
“Genomics is excited to be working with one of the world's leading research and development-based pharmaceutical companies in the rapidly growing area of genomic analysis. This exciting new area promises to potentially make a positive difference to medicine,” adds John Colenutt, CEO of Genomics.
Allergy Amplifier Implicated in Asthma Also Intensifies Food AllergyNews
Scientist who previously reported that a small protein, aptly named histamine-releasing factor, played a pro-inflammatory role in asthma have now shown that it also serves as a “food allergy amplifier”. This work paves the way for blood tests to predict which patients will respond to allergy therapy, and strongly supports the idea that drugs designed to block HRF could prevent food allergy attacks.READ MORE
Researchers Discover Mutation That Appears to Protect Against Multiple Aspects of Biological AgingNews
The first genetic mutation that appears to protect against multiple aspects of biological aging in humans has been discovered in an extended family of Old Order Amish living in the vicinity of Berne, Indiana, report Northwestern Medicine scientists.READ MORE
Discovery of Immune Defense Mechanism Could Help Improve TreatmentsNews
Researchers have identified a previously unknown mechanism by which the responses of key cells of the immune system are regulated. The finding could inform research into improved treatments for allergies or chronic inflammatory diseases.READ MORE