Emerging Models: MicroRNAs in jute
News Jan 01, 2014
Jute (Corchorus spp.) is an important fibre crop in South Asia. This smallholder’s crop is vulnerable to a most devastating pathogen, Macrphomina phaseolina. It causes damping off, root rot and collar rot collectively known as stem rot, which results in up to 30% yield loss and low fibre quality. The pathogen first causes root rot under high soil temperature and low soil moisture (drought) conditions and then colonises physiologically altered stem causing stem rot at maturity, under favourable weather conditions. However, the molecular mechanisms underlying are unknown. Plant-pathogen-weather interface is regulated by a number of genes. Existing, probe-dependent gene regulation analysis methods require plant and pathogen cells to be physically separated. However, probe-independent RNA sequencing method allows plant and pathogen transcripts to be analysed simultaneously.
Previous work by the International Multiple Sclerosis Genetics Consortium (IMSGC) has identified 233 genetic risk variants. However, these only account for about 20% of overall disease risk, with the remaining genetic culprits proving elusive. A new study has tracked down four of these hard-to-find genes.READ MORE