Enhancement of Vitamin B6 Levels in Seeds through Metabolic Engineering
News Aug 20, 2009
The work demonstrates that it is feasible to enhance vitamin B6 content in seeds, the researchers say. Vitamin B6 is essential for all cellular organisms and is particularly renowned in the medical field as being involved in more bodily functions than any other single nutrient, according to the article. Two vitamin B6 biosynthetic enzymes, PDX1 and PDX2, have been identified recently, and the article says their discovery has made it possible to regulate B6 production.
The "metabolically engineered" GM plants that were developed at the Danforth Center "overexpress" one or both of these two enzymes. The research results are said to be particularly applicable for crop plants whose seeds are the major source of food or feed. The article can be viewed online at the link below.
Mechanism Controlling Multiple Sclerosis Risk IdentifiedNews
Researchers at Karolinska Institutet have now discovered a new mechanism of a major risk gene for multiple sclerosis (MS) that triggers disease through so-called epigenetic regulation. They also found a protective genetic variant that reduces the risk for MS through the same mechanism.
Antarctic Worm and Machine Learning Help Identify Cerebral Palsy EarlierNews
A research team has released a study in the peer-reviewed journal BMC Bioinformatics showing that DNA methylation patterns in circulating blood cells can be used to help identify spastic cerebral palsy (CP) patients. The technique which makes use of machine learning, data science and even analysis of Antarctic worms, raises hopes for earlier targeted CP therapies.
Ancient Syphilis Genomes Decoded for First TimeNews
Researchers recovered three genomes of the bacterium Treponema pallidum from skeletal remains from colonial-era Mexico, and were able to distinguish the subspecies that causes syphilis from the subspecies that causes yaws. It was not previously thought possible to recover DNA from this bacterium from ancient samples.