Fluidigm Announces Availability of its Summer 2010 Edition of ‘IFC Application Hotspot’ E-newsletter
News Jul 09, 2010
The Summer 2010 edition of the e-newsletter - IFC Application Hotspot from Fluidigm Corporation is now available free to download from http://www.fluidigm.com/newsletters/2010edition1_v5/2010edition1_v5.html.
Dedicated to advances in single-cell research the Summer 2010 issue of IFC Application Hotspot includes two customer application studies, a recorded video interview with the Genome Insitute of Singapore and a new single-cell gene expression protocol.
The first application study reports on how resolution of cell fate decisions can be revealed by single-cell gene expression analysis from zygote to blastocyst. Using Dynamic Array™ Integrated Fluidic Circuits (IFCs), and the mouse preimplantation embryo as a model, scientists from Genome Institute of Singapore applied single-cell analysis to study the expression dynamics of 48 genes across mutliple developmental time points. The described work illustrates the power of single-cell expression analysis to provide insight into developmental mechanisms.
The second application study describes how using Dynamic Array™ IFCs, scientists at Keio University analyzed the expression of various cadherin genes in long-term hematopoietic stem cells (HSCs) and subpopulations of the HSCs isolated from the endosteum to better understand cadherin function as it relates to HSC-niche interactions.
Dr Paul Robson, of the Genome Institute of Singapore, discusses in a video interview, his latest research on single-cell expression data which is crucial for a detailed molecular understanding of mammalian development from fertilization to embryo implantation. His research has direct impact on clinical applications in the areas of regenerative medicine and assisted reproduction.
Innate Reaction of Hematopoietic Stem Cells to Severe InfectionsNews
Researchers at the University of Zurich have shown for the first time that hematopoietic stem cells detect infectious agents themselves and begin to divide, without signals from growth factors.READ MORE
CRISPR Reveals New Targets for Promising Cancer DrugsNews
Novel screening method identifies new drug targets that could potentially enhance the effectiveness of PD-1 checkpoint inhibitors, a promising new class of cancer immunotherapy.READ MORE
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