Fox Chase Cancer Center Adopts Nexus Copy Number and Nexus Expression
News Feb 11, 2009
BioDiscovery Inc. has announced that Fox Chase Cancer Center’s Keystone Program in Blood Cell Development and Cancer has acquired a site license for Nexus Copy Number and Nexus Expression, two companion tools designed specifically for scientists working on DNA copy number and RNA expression analysis from microarray data.
The Keystone Program researchers are using Nexus Copy Number and Nexus Expression to help identify genes involved in blood cell development and transformation. Identification of such genes is important for further enhancement in treatment of cancers of the blood as genes involved in normal development are also likely to be involved in transformation of normal blood cells into cancerous cells.
Nexus Copy Number and Nexus Expression are complementary platform independent products supporting all array platforms including Agilent, Affymetrix, Illumina, Roche NimbleGen, and custom arrays. They can integrate data from thousands of arrays in a single project and provide an easy to use interface that allows exploration of data to generate biological knowledge with a few mouse clicks. Nexus Copy Number allows analysis of CGH and SNP arrays for single or multiple sample analysis and Nexus Expression provides analysis of gene expression arrays.
In a new study in cells, University of Illinois researchers have adapted CRISPR gene-editing technology to cause the cell’s internal machinery to skip over a small portion of a gene when transcribing it into a template for protein building. This gives researchers a way not only to eliminate a mutated gene sequence, but to influence how the gene is expressed and regulated.
Researchers published today a detailed description of the complete genome of bread wheat, the world's most widely-cultivated crop. This work will pave the way for the production of wheat varieties better adapted to climate challenges, with higher yields, enhanced nutritional quality and improved sustainability.