Galapagos Featured in Leading Drug Discovery Journal
News Oct 14, 2005
Galapagos NV has announced that an article presenting the Company's approach to target discovery will appear in the October 15, 2005 issue of Drug Discovery.
The paper, entitled “Biology calls the targets: combining RNAi and disease biology”, gives insight into how Galapagos applies its proprietary RNA interference technology.
Furthermore, the article explains how this biology-driven approach can be used to functionally validate drug targets for major human diseases.
“Galapagos has built extensive expertise in using RNAi to discover and validate novel drug targets in a wide range of disease areas,” said Onno van de Stolpe, CEO of Galapagos.
“Our scientists were invited to present our protein knock-down technology using adenovirus-based RNAi libraries to discover new targets in human primary cells.”
“There is particularly strong interest in RNAi in the pharmaceutical industry and we believe targets identified using our approach could improve overall success rates in the drug discovery process.”
“The confidence is underscored by the fact that our pharmaceutical partners have taken targets identified using this biology-driven strategy, forward into their internal drug discovery programs.”
Analytical Tool Predicts Disease-Causing GenesNews
Predicting genes that can cause disease due to the production of truncated or altered proteins that take on a new or different function, rather than those that lose their function, is now possible thanks to an international team of researchers that has developed a new analytical tool to effectively and efficiently predict such candidate genes.
Gene Regulator May Contribute to Protein Pileup in Exfoliation GlaucomaNews
Researchers are seeking factors that contribute to protein pileup in exfoliation glaucomaREAD MORE
Single Gene Change in Gut Bacteria Alters Host MetabolismNews
Scientists have found that deleting a single gene in a particular strain of gut bacteria causes changes in metabolism and reduced weight gain in mice. The research provides an important step towards understanding how the microbiome – the bacteria that live in our body – affects metabolism.READ MORE