GENEART Awarded Contract to Design Mammalian Gene Library for National Cancer Institute
News Jan 17, 2007
GENEART has announced that the company has been awarded a contract for the synthesis of 2,000 to 3,000 genes and 2,000 to 3,000 gene variants thereof. The expected order volume amounts up to USD 6.5 million.
The genes to be synthesized by GENEART will be added by the National Cancer Institute to the NIH’S collection of genes of humans and mice to provide an important resource for basic and biomedical research.
Within the scope of the Mammalian Gene Collection Program, the National Institutes of Health (NIH) has been working on creating a publicly accessible cloned gene library of humans and mice since 1999.
According to company, the goal of Mammalian Gene Collection is to include at least one defined full-length clone of each known gene sequence of these two species. The Mammalian Gene Collection is the largest publicly available cDNA library, and of crucial importance for molecular research in mammals.
The GENEART is to synthesize up to 3,000 genes and 3,000 gene variants for the Mammalian Gene Collection over the next eight to ten months. The subset to be synthesized mainly comprises genes which could not be obtained at all or only at significant higher cost by using conventional methods such as cDNA libraries or RT-PCR.
In treating inflammatory bowel disease (IBD), physicians can have a hard time telling which newly diagnosed patients have a high risk of severe inflammation or what therapies will be most effective. Now researchers report finding an epigenetic signature in patient cells that appears to predict inflammation risk in a serious type of IBD called Crohn’s disease.