Genome of Strawberry Revealed
News Nov 01, 2016
NRGene is the first ever to assemble the complex genome of a commercially grown strawberry.
Most plant, animal, and human genomes are diploid - containing two variants from each gene. The strawberry genome contains eight nearly identical copies of each gene, making the accurate phasing of each something that has never been done before – until NRGene’s DeNovoMAGICTM 3.0.
The octoploid, heterozygous strawberry genome was assembled using reads produced on Illumina sequencing technology and assembled by NRGene’s cloud-based DeNovoMAGICTM 3.0 software package in only two weeks.
“It’s exciting to see how NRGene’s analysis, combined with data from Illumina sequencers, can be used to quickly and affordably assemble complex genomes, like that of the strawberry,” said Ryan Rapp, Associate Director, Agrigenomics for Illumina. “We hope that this technology will make genomics accessible to agricultural researchers worldwide, helping to improve the food supply to make it more sustainable and efficient.”
NRGene’s DeNovoMAGICTM 3.0 delivers complete, highly accurate genome assemblies in the form of long, phased sequences using Illumina-based reads. As more genomes are generated, NRGene’s PanMAGICTM is used to compare the complete genome sequences of multiple individual samples to capture the broad genomic diversity, better pinpointing positive traits across all varieties.
“With the data from NRGene, strawberry breeders will be able to accelerate the release of better performing strawberry varieties, creating hardier, more disease-resistant varieties with longer shelf lives,” says Sachiko Isobe, head of the plant genomics and genetics laboratory at Japan’s Kazusa DNA Research Institute.
NRGene has delivered the first bread wheat, Emmer wheat, and durum wheat genomes; dozens of new maize, soybean, cotton, and canola genomes; and is delivering more accurate versions of previously mapped genomes built on older, more inefficient technologies.
“The strawberry assembly demonstrates that even the most complex genomes can be mapped quickly and accurately,” says Gil Ronen, CEO of NRGene. “The ultimate value in our technology is that it can be deployed to analyze and assemble any genome across all species.”
The project was done in cooperation with Japan’s Kazusa DNA Research Institute and supported in part by Japan’s Ministry of Agriculture, Forestry and Fisheries.
"Genetic Jenga" Helps Understand How Our Genes Control Our CellsNews
To fully understand how our cells work, we can't focus on just one gene, but must instead look at combinations of genes. Researchers have published a study which knocked out multiple genes, like removing bricks from a Jenga tower, to better understand how they work together.READ MORE
Southeast Asian Nomads Have Evolved to Hunt Fish UnderwaterNews
The human spleen can release oxygenated blood cells to allow more time underwater without breathing. A new study has identified that the "Sea Nomad" Bajau people of Indonesia have evolved larger spleens that would allow them to remain underwater for longer.READ MORE
Gene Therapy Could End Transfusions for Blood Disorder PatientsNews
Beta-thalassemia patients need a regular dose of red blood cells transfused into their body. A new gene therapy that edits faulty genes in the patients' cells could end this monthly ritual.READ MORE
Comments | 0 ADD COMMENT
International Conference on Epigenetics and Epitranscriptomics
Sep 17 - Sep 18, 2018