Grant to TSRI-Led Consortium Increased by $87M
News Oct 06, 2016
The National Institutes of Health (NIH), as part of its national Precision Medicine Initiative (PMI) Cohort Program, has expanded a five-year funding award to The Scripps Research Institute (TSRI) from $120 million to $207 million.
The award marks a significant increase in scope from the initial award announced in July and provides additional details about the network of partners in the TSRI-led consortium.
“The size of this award underscores the critical nature of this research in improving our ability to prevent and treat disease,” said TSRI President Peter Schultz. “We are thrilled to be part of such a major undertaking and look forward to supporting Dr. Eric Topol in leading this unprecedented project.”
Topol, who is director of the Scripps Translational Science Institute (STSI), professor of genomics at TSRI and chief academic officer at Scripps Health, will direct the award as part of the PMI Cohort Program, which seeks to engage one million or more U.S. participants in a historic medical research effort aimed at improving the ability to prevent and treat disease based on individual differences in lifestyle, environment and genetics.
STSI is a National Institutes of Health-sponsored site led by TSRI and Scripps Health. This innovative research partnership is leading the effort to translate wireless and genetic medical technologies into high-quality, cost-effective treatments and diagnostics for patients.
The new award expands the group’s role in overseeing the enrollment of 350,000 “direct volunteers,” individuals interested in joining the PMI research study directly rather than through a healthcare provider organization. In addition, the award funds the creation of a Participant Technologies Center (PTC) to develop, test, maintain and upgrade the mobile applications and technology platform used to enroll, consent, collect data from, communicate with and retain participants. The PTC will also develop parallel platforms to deliver these same functions to those without smartphones.
“We are exceptionally fortunate to be working with an unparalleled group of partners and to be able to leverage the strengths of these leaders from a broad spectrum of sectors—pharmaceutical companies and health insurers to wireless technology experts and mobile application developers,” said Topol. “The depth and breadth of expertise of these organizations will be invaluable to our goal of advancing individualized medicine at a national level.”
The BuzzBuster: Could Gene Silencing Help Silence the Housefly?News
Gene silencing dsRNA technology can reduce housefly fertility, showing promise as a pest-control method.READ MORE
Researchers Zoom in on DNA Code Being Read in CellsNews
Scientists have unveiled incredible images of how the DNA code is read and interpreted – revealing new detail about one of the fundamental processes of life. The mechanism for reading DNA and decoding it to build proteins for their needs is common to all animals and plants, and is often hijacked by cancer. The discovery of exactly how the molecular mechanism works, could open up new approaches to cancer treatment.READ MORE
LogicTRN Model Illuminates Regulatory Gene FrameworkNews
A newly devised algorithm called LogicTRN has the potential to unravel the complexities of genetic regulation.READ MORE