Immunexpress Releases Key Performance Data on SeptiCyte®
News Dec 11, 2015
SeptiCyte®Lab is a rapid molecular assay that measures a patient’s gene expression level to differentiate between sepsis and infection-negative systemic inflammation.
The manuscript describes the identification of a classifier to accurately discriminate sepsis patients from patients with non-septic inflammation and the conversion of the classifier to RT-qPCR format which is the basis of the SeptiCyte® technology. The study details the validation of the technology across five independent patient cohorts and demonstrates clinical performance that outperforms clinical parameters including procalcitonin.
“Current technologies for the diagnosis of sepsis that seek to identify the causative pathogen are slow and frequently result in false negatives,” said Roslyn Brandon, President and CEO of Immunexpress. “Our technology, described today in PLOS Medicine, examines the host-response and can provide a probability of sepsis in 100% of cases just a few hours after a physician’s initial suspicion of sepsis. We look forward to sharing data from our prospective FDA regulatory trials of SeptiCyte® next year.”
Hay Fever Risk Genes Overlap with Autoimmune DiseaseNews
In a large international study involving almost 900,000 participants, researchers from the University of Copenhagen and COPSAC have found new risk genes for hay fever. It is the largest genetic study so far on this type of allergy, which affects millions of people around the world.READ MORE
Hidden Signals in RNAs Regulate Protein SynthesisNews
Scientists have long known that RNA encodes instructions to make proteins. In a new study published in Nature, scientists describe how the protein-making machinery identifies alternative initiation sites from which to start protein synthesis.READ MORE
ExPecto Patronum! Magical Machine Learning Tool Summons DNA Dark Matter DataNews
A new machine learning framework, dubbed ExPecto, can predict the effects of mutations in the so-called “dark matter” regions of the human genome. ExPecto pinpoints how mutations can disrupt the way genes turn on and off throughout your body.