Indian Scientists Sequence Neem Tree Genome

A team of ten researchers at Ganit Labs — an integrated genomics lab in Bangalore set up earlier this year under a public-private partnership between Institute of Bioinformatics and Applied Biotechnology and Strand Life Sciences, a bioinformatics company — has successfully sequenced the genome of the plant known for its medicinal properties.

“This is the first time the genome of a higher organism has been sequenced in India,” the head of Ganit Labs Binay Panda told a press conference Thursday.

Researchers in the US and elsewhere have sequenced genomes of several complex organisms but neem plant is not one of them.

“We have traditionally known the medicinal properties of neem,” Panda said. “Understanding its genetic complexity will help in developing agriculturally important compounds and pharmaceuticals. For instance, pesticidal compound Azadirachtin is found in neem seeds in wildly varying concentrations. With genetic understanding and engineering, Azadirachtin content in neem could potentially be increased and normalised.”

 The findings from the project, a results of extensive interdisciplinary collaboration, will be sent to a peer-reviewed journal for review and publication.

Translational genomics aside, the study has also thrown up scientifically significant findings. “For instance, some of the genetic data suggests similarities with citrus family, which is unexpected given that neem is a woody tree,” Panda said, adding that scientists were yet to understand the evolutionary context of neem tree.