ISB Adopts Kreatech's ULS™ Nucleic Acid Labeling Technology

The continuing scientific collaboration between the Institute of Systems Biology and Kreatech's product development team has resulted in an arrangement between Kreatech and the ISB for the use of Kreatech's commercial products.

Kreatech's platinum based "Universal Linkage System" (ULS™), a non-enzymatic way of labeling nucleic acids with detectable molecules such as fluorophores, has been adopted by Dr. Nitin Baliga's research group and is now the preferred labeling method for both bacterial gene expression profiling and Chip on Chip assays that have been developed at the ISB.

Currently available kits from Kreatech are optimized for labeling of amplified RNA for gene-expression analysis and for labeling of genomic DNA for microarray based comparative genomic hybridization (arrayCGH).

This collaboration with the ISB will help Kreatech to position the ULS technology in new application areas.

"We are pleased and very proud with the fact that a renowned institute like the Institute of Systems Biology has made the switch to our technology", says Alexander Altink, Kreatech's CEO.

The labeling kits used by the ISB include the purification columns (KREApure), blocking buffer (KREAblock) and ULS bound with Dyomics' DY Dyes.

"We have been working with this technology for a while and we like both the reproducible labeling efficiencies as well as the one-step purification of labeled material", says Dr. Nitin Baliga, Assistant Professor at the ISB.