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Latest Advancements in Cellular DNA Repair Revealed


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Renowned biochemist, Elaine L. Jacobson, Ph.D., will discuss the latest advancements in cellular DNA repair at the Mentor Paragon Forum Advanced Symposium on Breast and Facial Aesthetics on Sunday, October 8, 2006, in San Francisco, CA.

Dr. Jacobson will present her discoveries in relation to the role of niacin and niacin-derived molecules in cellular response to genetic damage and the prevention of photodamage in the skin.

Her presentation will include key findings from her research demonstrating that niacin and its derivatives are crucial in preventing cellular DNA damage, enhancing DNA repair, maintaining genomic integrity and, ultimately, strengthening the skin's protective barrier.

Dr. Jacobson's research, performed in collaboration with Dr. Myron K. Jacobson, has been continuously funded by the National Institutes of Health for 28 years, and has led to 150 published papers and invited book chapters, and 25 patent applications.

Together, their research has led to the discovery of functions of niacin in skin biology, and the development of novel compounds designed for topical delivery of niacin.

One of these compounds has proven so effective that it has been selected by the National Cancer Institute for evaluation as a possible skin cancer prevention agent under the Rapid Access to Prevention Intervention Development (RAPID) program.

Dr. Jacobson is a Professor of Medicinal Chemistry of the College of Pharmacy and a member of the Arizona Cancer Center of the University of Arizona. She is also a principal scientist of Niadyne, Inc.

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