Mapping the Range of Genetic Diversity in Asia and Genetic Origins of Asian Populations
News Apr 12, 2010
IGIB participated in the study by the Pan-Asian SNP Consortium of the Human Genome Organization (HUGO) which recently analyzed human genetic diversity in 73 Southeast Asian and East Asian populations.
Besides IGIB scientists, the consortium of 90 scientists has participants from Singapore, India, China, Japan, Thailand, Philippines, South Korea, Taiwan, Japan and Indonesia. The study has important implications, especially in understanding human migration and for the study of genetics and diseases.
The study showed that genetic ancestry was highly correlated with ethnic and linguistic groups. There was a clear increase in genetic diversity from northern to southern latitudes.
The study also suggested that there was one major inflow of human migration into Asia arising from Southeast Asia, rather than multiple inflows from both southern and northern routes as proposed before. This indicates that Southeast Asia was the major geographic source of East Asian and North Asian populations. This study further highlights the need for genetic stratification when conducting genetic and pharmacogenomic studies in this continent.
Chinese researchers have developed interfacially polymerized porous polymer particles for low- abundance glycopeptide separation. These polymer particles - with hydrophilic-hydrophobic heterostructured nanopores - can separate low-abundance glycopeptides from complex biological samples with high-abundance background molecules efficiently.