Mayo, Baylor Collaborate
News May 15, 2015
A new sequencing study will look at 69 genes associated with drug reactions and drug metabolism in 10,000 patients in the Mayo biobank to predict any potentially adverse reactions or ineffectual drug response. Any findings relevant to a patient will be noted in the person's electronic medical record, which the Mayo Clinic said could preempt adverse drug reactions and ineffective treatments. Baylor's Human Genome Sequencing Center will provide sequencing services for the study as well as collaborate on analyzing the data to find new clinically relevant genomic variants associated with drug response.
The study is notable because it will sequence patients' genomes, rather than genotype them, Richard Weinshilboum, director of Mayo Clinic's Center for Individualized Medicine pharmacogenomics program, told GenomeWeb.
The collaboration is an example "of how a partnership between a genome center and a premier clinical group can speed the translation of valuable genomic tests into useful advances in patient care," Richard Gibbs, director of the Human Genome Sequencing Center at Baylor, said in a statement.
The Mayo Clinic Center for the Science of Health Care Delivery will simultaneously analyze the results of the study and track health outcomes to see if sequencing genes related to drug response and putting that genomic data in medical records can improve care for patients.
This month, Baylor announced it would explore the possibility of performing clinical exome sequencing in adults.
Schizophrenics' Blood Contains RNA From More MicrobesNews
The blood of schizophrenia patients features genetic material from more types of microorganisms than that of people without the debilitating mental illness, research at Oregon State University has found. What’s not known is whether that’s a cause or effect of the severe, chronic condition that strikes about one person in 100.READ MORE
Faulty Gene Leads to Alcohol-Induced Heart FailureNews
A faulty gene interacts with alcohol to accelerate heart failure in susceptible patients, a study suggests. This dangerous interaction can occur even when only moderate amounts of alcohol have been consumed.READ MORE
Tiny Particles Carry Tumor Shrinking Drugs into the BrainNews
MIT researchers have now devised a new drug-delivering nanoparticle that could offer a better way to treat glioblastoma. The particles, which carry two different drugs, are designed so that they can easily cross the blood-brain barrier and bind directly to tumor cells.READ MORE
Comments | 0 ADD COMMENT
2nd Annual Artificial Intelligence in Drug Development Congress
Sep 20 - Sep 21, 2018