We've updated our Privacy Policy to make it clearer how we use your personal data.

We use cookies to provide you with a better experience. You can read our Cookie Policy here.

Advertisement
More Patents Granted in Europe and the US Significantly Strengthen Benitec’s Dominant Global Intellectual Property Position in Gene Silencing
News

More Patents Granted in Europe and the US Significantly Strengthen Benitec’s Dominant Global Intellectual Property Position in Gene Silencing

More Patents Granted in Europe and the US Significantly Strengthen Benitec’s Dominant Global Intellectual Property Position in Gene Silencing
News

More Patents Granted in Europe and the US Significantly Strengthen Benitec’s Dominant Global Intellectual Property Position in Gene Silencing

Read time:
 

Want a FREE PDF version of This News Story?

Complete the form below and we will email you a PDF version of "More Patents Granted in Europe and the US Significantly Strengthen Benitec’s Dominant Global Intellectual Property Position in Gene Silencing"

First Name*
Last Name*
Email Address*
Country*
Company Type*
Job Function*
Would you like to receive further email communication from Technology Networks?

Technology Networks Ltd. needs the contact information you provide to us to contact you about our products and services. You may unsubscribe from these communications at any time. For information on how to unsubscribe, as well as our privacy practices and commitment to protecting your privacy, check out our Privacy Policy

Benitec Ltd has announced that two further patents owned or licensed exclusively by Benitec have been granted or allowed in Europe and the US respectively.

The CSIRO-owned patent EP1068311-B1 (“Methods and Means for Obtaining Modified Phenotypes”), for which Benitec is the exclusive licensee in the field of human therapeutics, has been granted in Europe. The grant of EP1068311 was published on 27 April 2011.

The patent includes key claims to silencing of genes by using either a hairpin RNA having a double-stranded RNA portion, or a DNA molecule which forms the hairpin RNA, and which targets the coding region of a gene incorporated in a cell.

The double-stranded RNA portion is composed of a sense and an antisense nucleotide sequence, each of which are at least 10 consecutive nucleotides long, and which are 75 to 100% identical to a region of the target gene sequence.

The European patent provides broad protection for Benitec’s gene silencing technology using DNA directed RNA interference (ddRNAi). This patent granting is timely as Dr French will be presenting Benitec’s investment case at the BioEquity Conference in Paris on 23 May 2011, as announced earlier.

In addition, the USPTO has recently issued a Notice of Allowance (on 14 April 2011) for the Benitec-owned patent application No. 11/355516 entitled “RNAi expression constructs with liver-specific enhancer/promoter”, with a patent term adjustment of 81 days. The claims cover a ddRNAi therapeutic capable of producing three or more gene silencing molecules specifically targeting the Hepatitis C Virus.

The construct comprises one or more liver specific DNA machinery elements. Methods of using the construct are also included. Benitec have licensed the use of ddRNAi for targeting Hepatitis C to Tacere Therapeutics Inc., who in turn have sub-licensed the technology to Pfizer for clinical development of a ddRNAi therapeutic for Hepatitis C, a disease that affects up to 200 million people worldwide.

With the granting of the CSIRO European patent, which covers the broad use of ddRNAi, and allowance of the US patent covering the use of a multi ddRNAi approach for the treatment of hepatitis C, Benitec’s owned and exclusively licensed patent estate continues to reinforce Benitec’s dominant position in the field of gene silencing.

Benitec is focusing on demonstrating the power and the potential of these and the other (more than 100) patents and patent applications to be the basis of a new generation of transformational human therapeutics to treat and cure a wide range of medical conditions.

Advertisement