National Heart, Lung, and Blood Institute Announces new Strategic Plan
News Dec 04, 2007
The National Heart, Lung, and Blood Institute of the National Institutes of Health has announced a new strategic plan to guide its next decade of research, training, and education to reduce the national burden of cardiovascular, lung, blood, and sleep disorders.
"This plan sets the institute on a trajectory toward preempting disease by using emerging and sophisticated research approaches, adapting to a rapidly changing health care environment, and remaining flexible to invest in new research opportunities that offer the best potential for improving the nation’s health," said Elizabeth G. Nabel, M.D, Director, NHLBI.
The plan sets forth three major goals that cover the scientific continuum from bench to bedside and address basic, clinical, and translational research. Realizing the future envisioned in the plan will require collaboration with many other organizations, both public and private, and with other agencies of the Federal government.
Powerful new research approaches in the fields of genetics, genomics, and imaging provide unprecedented opportunities to achieve the one of the three goals: to increase understanding of the molecular and physiological basis of health and disease.
An example of a new program to address this goal is one that will link genetic data from long-standing groups of clinical study participants with data about their health indicators and characteristics, and then make the data available to researchers - with appropriate privacy safeguards.
A second goal is to enhance knowledge of the clinical mechanisms of disease and thereby identify better approaches to prevention, diagnosis, and treatment. Addressing this goal will be enabled by new clinical research networks designed to investigate innovative approaches to promote establishment of standard treatment protocols to test new basic science discoveries and then foster rapid dissemination of research findings to health care professionals and the public.
The final goal is to improve the translation of research into practice for the benefit of personal and public health by seeking a better understanding of the processes for health behavior change. Approaches to be employed include those that will tie the development of guidelines for clinical practice to up-do-date scientific evidence and then promote their use through appropriately designed public education programs.
"We must close the gap between scientific discovery and the effective dissemination of research results into daily health practice, and then use the lessons learned from that effort to stimulate further scientific research," said Nabel.
New Cell-weighing Technique Helps Predict How Drugs Affect Cancer CellsNews
Researchers at MIT have now shown that they can use a new type of measurement to predict how drugs will affect cancer cells taken from multiple-myeloma patients.READ MORE
Researchers Discover Mutation That Appears to Protect Against Multiple Aspects of Biological AgingNews
The first genetic mutation that appears to protect against multiple aspects of biological aging in humans has been discovered in an extended family of Old Order Amish living in the vicinity of Berne, Indiana, report Northwestern Medicine scientists.READ MORE
Defects in Cell’s ‘Waste Disposal System’ Linked to Parkinson’sNews
An international study has shed new light on the genetic factors associated with Parkinson’s disease, pointing at a group of lysosomal storage disorder genes as potential major contributors to the onset and progression of this common neurodegenerative disorder.READ MORE