New Advancements from Ambion in Data Analysis for MicroRNA Profiling
News Feb 21, 2006
Ambion Services has announced the release of an expression profiling service specifically for microRNA analysis that surpasses any other offering currently in the market.
A growing body of evidence suggests that microRNAs could be useful in diagnosis and treatment for a range of diseases.
Based on technology from Ambion, expression profiles generated from this service are sensitive and representative of the microRNAs present in samples.
Ambion Services has further advanced this technology, developing proprietary algorithms for data normalization and scaling that are key to delivering meaningful expression information.
Ambion Services tailored their comprehensive data analysis algorithms and statistical approaches for microRNA profiling because many of the fundamental assumptions used for messengerRNA analysis do not apply.
According to Scott Hunicke-Smith, Ph.D., Vice President of Ambion Services, "One cannot rely on mRNA expression profiling experience when performing microRNA profiling data analysis."
"We have focused our development efforts, utilizing Ambion's extensive database of microRNA expression data, on the unique tools required for miRNA analysis."
In treating inflammatory bowel disease (IBD), physicians can have a hard time telling which newly diagnosed patients have a high risk of severe inflammation or what therapies will be most effective. Now researchers report finding an epigenetic signature in patient cells that appears to predict inflammation risk in a serious type of IBD called Crohn’s disease.