Novel Insights into the Control of Gene Expression
News Jul 02, 2014
Oxford Gene Technology (OGT) has made the latest in its series of educational webinars available to watch online at www.ogt.com/webinars.
RNA-Seq is proving to be a valuable tool for enabling researchers to gain greater insight into changes in gene expression during disease initiation, progression, treatment and the development of drug resistance. In his presentation, Dr Jones discusses his use of Drosophila melanogaster as a model organism for investigating the control of gene expression via mRNA degradation and explores a range of interesting findings from the work that OGT carried out via its Genefficiency™ RNA-Seq Service. These have given new insights into the number of upregulated and downregulated genes in different null mutants and the degree to which expression of these genes changes. This was made easier by OGT’s interactive reporting, which enables simple and rapid understanding of RNA-Seq data without the need for in-house bioinformatics support.
The webinar, “Developing new insights into gene expression using RNA-Seq,” can be viewed below
In treating inflammatory bowel disease (IBD), physicians can have a hard time telling which newly diagnosed patients have a high risk of severe inflammation or what therapies will be most effective. Now researchers report finding an epigenetic signature in patient cells that appears to predict inflammation risk in a serious type of IBD called Crohn’s disease.