Nucleis will Present its RNAi Technology
News Sep 28, 2005
Nucleis has announced that it has offered knock down (RNAi) in vivo mouse model and is currently developing alternatives for conditional and inducible in vivo knock down (RNAi) expression.
Nucleis thanks to a proprietary innovative technology called Speedy Mouse Technology which allows the generation of models in two months.
Speedy Mouse RNAi Technology is based on targeted transgenesis of short hairpin RNA construct into hprt permissive locus of proprietary ES cells, called BPES cells.
These cells demonstrate high potency to colonize wild type blastocyst leading to 100% chimeric mice with 100% germ line transmission.
Single copy integration of shRNA constructs through targeted transgenesis in BPES cells appears to be as efficient as random transgenesis but powerful in term of time, reproducibility and predictability.
Exclusive results of the efficiency, stability and inheritability of the Speedy Mouse® RNAi Technology will be presented at “RNAi Europe meeting” in Amsterdam on September 29th and later in Boston on October 18th for the 4th Annual Discovery on Target.
Schizophrenics' Blood Contains RNA From More MicrobesNews
The blood of schizophrenia patients features genetic material from more types of microorganisms than that of people without the debilitating mental illness, research at Oregon State University has found. What’s not known is whether that’s a cause or effect of the severe, chronic condition that strikes about one person in 100.READ MORE
Faulty Gene Leads to Alcohol-Induced Heart FailureNews
A faulty gene interacts with alcohol to accelerate heart failure in susceptible patients, a study suggests. This dangerous interaction can occur even when only moderate amounts of alcohol have been consumed.READ MORE
Genetic Diversity Helps Protect Against DiseaseNews
Why do populations have genetic diversity when 'Survival of the Fittest' suggests that only one gene pool should thrive? It's a question that is hard to answer experimentally. A new study looking at evolutionary change in real time in tiny fungal parasites may provide a solution.