Phase I and II SBIR Grants Issued to Biosearch
News Jun 18, 2007
Biosearch Technologies, Inc. (BTI) has announced that two staff scientists have been awarded Small Business Innovation Research (SBIR) Grants by the National Institutes of Health (NIH) in Bethesda, Maryland.
The first, a $750,000 SBIR Phase II grant funded by the National Institute of General Medical Sciences (NIGMS), will fund the development of fluorescence-based reporter assays incorporating a recently discovered azoreductase that has been shown to release high-quality fluorescent signals. This work has important implications for significantly increasing the data generated by existing high-throughput drug screening technologies through the multiplexing of two or more reporter assays in one screening run.
The second, a $100,000 SBIR Phase I grant again funded by the National Institute of General Medical Sciences (NIGMS), will fund the development of technology for engineering bacterial chromosomes utilizing synthetic DNA. Outgrowths of this technology will enable the facile engineering of bacterial strains for a variety of applications including bioremediation, natural products and biofuel production.
As genome editing technologies advance toward clinical therapies, they are raising hopes of a completely new way to treat disease. However, challenges need to be addressed before potential treatments can be widely used in patients. To tackle these challenges, the National Institutes of Health has launched the Somatic Cell Genome Editing program, which has awarded multiple grants including more than $3.6 million to assess the safety of genome editing in human cells and tissues.