Resolving Nitrogen-15 and Proton Chemical Shifts for the Mobile Segments of Elastin with Two-Dimensional NMR Spectroscopy

Using an artificial intestine they created, researchers have shown that the microbiome can quickly adapt from the bacterial equivalent of a typical western diet to one composed exclusively of dietary fats.

In treating inflammatory bowel disease (IBD), physicians can have a hard time telling which newly diagnosed patients have a high risk of severe inflammation or what therapies will be most effective. Now researchers report finding an epigenetic signature in patient cells that appears to predict inflammation risk in a serious type of IBD called Crohn’s disease.

Over the past several years, CRISPR-Cas9 has moved beyond the lab bench and into the public zeitgeist. Now, scientists from the Salk Institute are reporting for the first time the detailed molecular structure of CRISPR-Cas13d, a promising enzyme for emerging RNA-editing technology.