We've updated our Privacy Policy to make it clearer how we use your personal data.

We use cookies to provide you with a better experience, read our Cookie Policy

RNA Defense System Protects the Genome When it's Epigenetically Naked

News   Jul 03, 2017 | Original story from CSHL

 
RNA Defense System Protects the Genome When it's Epigenetically Naked

A transfer RNA (tRNA) molecule. Fragments of 18 and 22 nucleotides, snipped from a full-length tRNA in the region circled in red, act to defend the genome in embryonic cells in the interval before the young embryo is implanted in the mammalian uterus. The sequences are complementary to, and act to interfere with, a binding site called the PBS in retrotransposons that must be engaged for their activation. About 42% of the human genome consists of parasitic retrotransposon sequences, which epigenetic marks repress except during brief intervals of epigenetic reprogramming. This defense mechanism seems to be analogous to the piRNA defense system that protects the genome in germline cells. Image courtesy of Wikimedia Commons.

 
 
 

RELATED ARTICLES

Study Links Thyroid Cancer, Genetic Variations and Cell Phones

News

Radiation from cell phones is linked to higher rates of thyroid cancer among people with genetic variations in specific genes, a new study led by the Yale School of Public Health finds.

READ MORE

Genetic Profile Could Predict Chance of Type 2 Diabetes in Women With Gestational Diabetes

News

Women who go on to develop type 2 diabetes after having gestational, or pregnancy-related, diabetes are more likely to have particular genetic profiles, suggests an analysis by researchers at the National Institutes of Health and other institutions.

READ MORE

Unusually Large Viruses Found in Unexpected Places

News

Scientists have discovered hundreds of unusually large, bacteria-killing viruses with a complexity normally associated with living organisms.

READ MORE

 

To personalize the content you see on Technology Networks homepage, Log In or Subscribe for Free

LOGIN SUBSCRIBE FOR FREE