Roche Acquires Mirus to Advance Research in the Field of RNAi Delivery
News Jul 23, 2008
Roche and Mirus Bio Corporation announced that they have entered into a definitive agreement under which Roche will acquire Mirus Bio Corporation, a privately-owned US company based in Madison, Wisconsin, that focuses on the discovery and development of innovative nucleic acid based technologies, including a proprietary RNAi (Ribonucleic Acid interference) delivery platform.
Roche's mission is to find novel solutions for patients who suffer from difficult to treat diseases. RNAi therapeutics provides the capabilities to target complex diseases such as cancer, respiratory or metabolic disorders.
In 2007, Roche already announced a major alliance with the US-based company Alnylam Pharmaceuticals, Inc., which included the acquisition of Alnylam's European research site located in Kulmbach, Germany. This is now Roche's established Centre of Excellence for RNAi therapeutic research.
Under the terms of the agreement, Roche will fully acquire Mirus for USD 125 million and will maintain an RNAi research site in Madison. Mirus' transfection reagents business will be divested into a standalone business to be known as Mirus Bio LLC, without any anticipated effect on existing customers.
Employees will be offered a transition into their respective business unit. Closing of the transaction is subject to standard conditions. Completion is expected during the second half of 2008.
Bird and Turtle Chromosomes Help Identify Dinosaur DNANews
Researchers have used bird and turtle DNA to extrapolate the chromosome structure of their common ancestor that lived around 260 million years ago – 20 million years before the dinosaurs first emerged. They were then able to trace the evolution of avian and non-avian dinosaur DNA through to the present day.
Over 130 Glaucoma Gene Variants Could Help Predict BlindnessNews
An international study has identified 133 genetic variants that could help predict the risk of developing glaucoma, the world’s leading cause of incurable blindness. The findings are an advance in the fight to tackle the incurable, degenerative condition, which has virtually no symptoms in the early stages, and could lead to a genetic-based screening program.READ MORE
Yeast Study Performs Hundreds of Simultaneous CRISPR EditsNews
A new technique which can alter hundreds of different genes at once in baker's yeast could greatly speed up CRISPR-Cas9 editing and offer a way to perform high-throughput functional genomics.READ MORE