Roche and PerkinElmer have announced a new supply agreement for distribution of the NimbleGen CGX microarray workflow, for use in constitutional disease research.
Under this agreement, effective January 2012, PerkinElmer will assume responsibility from Roche for sales, service, and support of the CGX array workflow for most countries outside of the U.S. Roche will continue to sell this innovative workflow in the U.S. and other select markets.
This is a further evolution of the relationship between the two companies which started in 2009 with the development of a comprehensive cytogenetics array workflow.
The combined solution, the NimbleGen CGX array workflow, uses advanced microarray technologies from Roche with the cytogenetic-focused array design and analysis software developed from Signature Genomics (acquired by PerkinElmer in May 2010), which was the first laboratory to provide microarray-based cytogenetic testing in the U.S.
The workflow is a comprehensive microarray solution for the discovery and analysis of copy number variations associated with constitutional disorders for the cytogeneticsresearch market.
This optimized workflow consists of NimbleGen CGX microarrays, reagent kits, the NimbleGen Hybridization Systems, and Signature Genomics Genoglyphix® software for data analysis.
The NimbleGen CGX array design was developed by Signature Genomics based on the analysis of over 50,000 cytogenetic samples to ensure appropriate coverage of the cytogenetically relevant regions.
The arrays are available in multiple formats (3-, 6-, and 12-plex) to match the throughput requirements of the researcher.
According to Jim Corbett, President, Diagnostics, PerkinElmer, “We are delighted to continue our collaboration with Roche in helping to bring the benefits of a proven cytogenetics-based solution to researchers of new diagnostics outside of the US. We look forward to providing these diagnostics researchers with high-resolution, scalable and easy to use workflows to help them unlock DNA-based complexities of critical disease states.”
“This collaboration provides cytogenetics laboratories an array workflow with robust data, a quick and easy workflow, and powerful analysis tools,” stated Frank Pitzer, CEO of Roche NimbleGen.
Pitzer continued, “PerkinElmer’s global experience in the genetic screening market and expertise in the field of cytogenetics is an ideal match for Roche NimbleGen’s innovative array technologies.”