Scientists Publish Results on Sigma-Aldrich's shRNA Library in Cell
News Apr 13, 2006
The publication reported the creation of a lentiviral shRNA library to knock down genes for genome-wide screening.
The library, now commercially available as Sigma-Aldrich's lentiviral MISSION™ shRNA library, targets 19,000 human and mouse genes and offers a new resource for somatic cell genetics providing new insights in loss-of- function screens in mammalian cells.
It will facilitate comprehensive screening efforts and will be useful in enabling arrayed screens that focus on mouse or human primary cells.
Schizophrenics' Blood Contains RNA From More MicrobesNews
The blood of schizophrenia patients features genetic material from more types of microorganisms than that of people without the debilitating mental illness, research at Oregon State University has found. What’s not known is whether that’s a cause or effect of the severe, chronic condition that strikes about one person in 100.READ MORE
Faulty Gene Leads to Alcohol-Induced Heart FailureNews
A faulty gene interacts with alcohol to accelerate heart failure in susceptible patients, a study suggests. This dangerous interaction can occur even when only moderate amounts of alcohol have been consumed.READ MORE
Genetic Diversity Helps Protect Against DiseaseNews
Why do populations have genetic diversity when 'Survival of the Fittest' suggests that only one gene pool should thrive? It's a question that is hard to answer experimentally. A new study looking at evolutionary change in real time in tiny fungal parasites may provide a solution.