ServiceXS Introduces new Line of Products and Services based on DNAFORM’s Cloning and CAGE Technology
News Oct 06, 2008
DNAFORM and ServiceXS B.V. have announced that the companies signed an agreement in which ServiceXS is appointed as exclusive distributor for DNAFORM’s products and services using DNAFORM’s proprietary cloning and CAGE technology in the Benelux.
On October 1st, ServiceXS officially launched two new services: DeepCAGE and NormRNA sequencing. DeepCAGE, a combination of DNAFORM’s proprietary CAGE technology® and ServiceXS’ next-generation sequencing service, facilitates genome-wide analysis of 5’-ends of mRNA molecules.
Currently, DeepCAGE allows sequencing of 5 million 5’ RNA-ends in a single run. DeepCAGE offers a solution to study transcription initiation and regulation at a whole-genome level. Furthermore, DeepCAGE enables promoter mapping.
The NormRNA sequencing service combines DNAFORM’s technology to create full-length, normalized cDNA Libraries with ServiceXS’ next-generation sequencing service, enabling genome-wide analysis of the transcriptome.
Applications include whole transcript profiling in basic genome projects, analysis of RNA splice variants in fundamental research, as well as a wide range of specialized applications like the discovery of new RNA-RNA fusions in oncology research. In addition, DNAFORM full-length cDNA libraries provide access to cDNA clones for newly discovered transcripts for further functional analysis.
In a new study in cells, University of Illinois researchers have adapted CRISPR gene-editing technology to cause the cell’s internal machinery to skip over a small portion of a gene when transcribing it into a template for protein building. This gives researchers a way not only to eliminate a mutated gene sequence, but to influence how the gene is expressed and regulated.
Researchers published today a detailed description of the complete genome of bread wheat, the world's most widely-cultivated crop. This work will pave the way for the production of wheat varieties better adapted to climate challenges, with higher yields, enhanced nutritional quality and improved sustainability.